Autor: |
Jessica L. Britt, Maslyn A. Greene, Sarah A. Wilbanks, J. Keith Bertrand, James L. Klotz, William Bridges, Glen Aiken, John G. Andrae, Susan K. Duckett |
Jazyk: |
angličtina |
Rok vydání: |
2020 |
Předmět: |
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Zdroj: |
Animals, Vol 10, Iss 12, p 2291 (2020) |
Druh dokumentu: |
article |
ISSN: |
2076-2615 |
DOI: |
10.3390/ani10122291 |
Popis: |
Endophyte-infected tall fescue (E+) produces ergovaline and ergovalinine, which are mycotoxins that act as dopamine agonists to suppress prolactin and induce vasoconstriction. The experiment was designed as a 3 × 2 × 2 factorial with DRD2 genotype (AA, AG, GG), fescue seed (endophyte-free, E− or endophyte-infected, E+), stage of gestation (MID, d (day) 35–85; LATE, d 86–parturition) and all interactions in the model. Pregnant Suffolk ewes (n = 60) were stratified by genotype and fed E+ or E− seed in a total mixed ration according to treatment assignment. Serum prolactin concentrations were lower (p < 0.05) in ewes fed E+ seed but did not differ by maternal DRD2 genotype or two-way interaction. Lamb birth weight was lower (p < 0.05) in ewes fed E+ seed in last trimester. Pre-weaning growth rate, milk production and total weaning weight was reduced (p < 0.05) in ewes fed E+ fescue seed during MID and LATE gestation. Ingestion of ergovaline/ergovalinine in last trimester reduces lamb birth weight; however, lamb growth rate, milk production and total weaning weight are reduced in all ewes fed E+ during mid and last trimester. |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
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