Integration of interictal EEG source localization in presurgical epilepsy evaluation – A single‐center prospective study

Autor: Gadi Miron, Thomas Baag, Kara Götz, Martin Holtkamp, Bernd J. Vorderwülbecke
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Epilepsia Open, Vol 8, Iss 3, Pp 877-887 (2023)
Druh dokumentu: article
ISSN: 2470-9239
DOI: 10.1002/epi4.12754
Popis: Abstract Objective To investigate cost in working hours for initial integration of interictal EEG source localization (ESL) into clinical practice of a tertiary epilepsy center, and to examine concordance of results obtained with three different ESL pipelines. Methods This prospective study covered the first year of using ESL in the Epilepsy‐Center Berlin‐Brandenburg. Patients aged ≥14 years with drug‐resistant focal epilepsy referred for noninvasive presurgical evaluation were included. Interictal ESL was based on low‐density EEG and individual head models. Source maxima were obtained from two freely available software packages and one commercial provider. One physician and computer scientist documented their working hours for setting up and processing ESL. Additionally, a survey was conducted among epilepsy centers in Germany to assess the current role of ESL in presurgical evaluation. Results Of 40 patients included, 22 (55%) had enough interictal spikes for ESL. The physician's working times decreased from median 4.7 hours [interquartile range 3.9‐6.4] in the first third of cases to 2.0 hours [1.9‐2.4] in the remaining two thirds; P
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