Role of biomarkers in community-acquired pneumonia management

Autor: Bahaeddin Onur, Hakan Barış Demirbas, Arif Gulmez
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Journal of Acute Disease, Vol 13, Iss 3, Pp 87-92 (2024)
Druh dokumentu: article
ISSN: 2221-6189
2589-5516
DOI: 10.4103/jad.jad_65_24
Popis: Community-acquired pneumonia (CAP) poses a significant global health threat, particularly affecting vulnerable populations. Biomarkers and scoring systems play a crucial role in diagnosing, assessing severity, and guiding treatment decisions for CAP patients. Biomarkers like C reactive protein, procalcitonin, and the neutrophil-to-lymphocyte ratio aid in diagnosis and severity assessment, while scoring systems such as CURB-65 and Pneumonia Severity Index classify patients into risk categories. Emerging biomarkers (uremia, elevated respiratory rate, hypotension, and age ≥ 65) like serum amyloid A and S100 proteins show promise in predicting disease severity and prognosis. However, further research is needed to determine their precise roles and clinical utility in CAP management.
Databáze: Directory of Open Access Journals