Adiaspiromicose humana: lesões cicatriciais em linfonodos do mediastino Human adiaspiromycosis: cicatricial lesions in mediastinal lymph nodes
| Autor: | Mário A.P. Moraes, Maria Iolanda Gomes |
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| Jazyk: | angličtina |
| Rok vydání: | 2004 |
| Předmět: | |
| Zdroj: | Revista da Sociedade Brasileira de Medicina Tropical, Vol 37, Iss 2, Pp 177-178 (2004) |
| Druh dokumentu: | article |
| ISSN: | 0037-8682 1678-9849 |
| DOI: | 10.1590/S0037-86822004000200013 |
| Popis: | Em paciente de 60 anos, sexo masculino, com diagnóstico radiográfico de massa tumoral no pulmão direito - depois reconhecida, por meio de biópsia transbrônquica, como de natureza maligna -, não se descobriu qualquer evidência tomográfica de metástases a distância. Resolveu-se então, para fins de estadiamento da neoplasia, obter material de linfonodos mediastinais. O exame microscópico desse material não demonstrou invasão neoplásica, mas revelou a presença de granulomas em avançado estádio de fibrose, contendo raras estruturas redondas, vazias, de parede espessa e, quase sempre, colapsada, que foram reconhecidas como adiaconídios de Emmonsia crescens. Havia ainda, nos cortes histológicos, grande quantidade de pigmento antracótico.Chest roentgenogram of a sixty-year-old male patient, revealed a tumoral mass in the right lung, that was later demonstrated by transbronchial biopsy, to be a bronchogenic adenocarcinoma. There was no tomographic evidence of distant metastasis, however, in order to assess the mediastinal involvement for staging of the tumor, biopsies from the regional lymph nodes were obtained. Microscopic examination of the sample tissues failed to show any metastatic lesion, but, unexpectedly, revealed the presence of cicatricial granulomas in an advanced stage of fibrosis. They contained a few round, empty and collapsed corpuscles, limited by a thick PAS-positive, membrane. These structures were identified as adiaconidia of Emmonsia crescens, the etiological agent of human adiaspiromycosis. In the tissue sections, a large amount of carbon dust (anthracosis) was also seen. |
| Databáze: | Directory of Open Access Journals |
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