Animal Models of Ischemic Stroke with Different Forms of Middle Cerebral Artery Occlusion
Autor: | Lang Zeng, Shengqi Hu, Lingcheng Zeng, Rudong Chen, Hua Li, Jiasheng Yu, Hongkuan Yang |
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Jazyk: | angličtina |
Rok vydání: | 2023 |
Předmět: | |
Zdroj: | Brain Sciences, Vol 13, Iss 7, p 1007 (2023) |
Druh dokumentu: | article |
ISSN: | 2076-3425 34454470 |
DOI: | 10.3390/brainsci13071007 |
Popis: | Ischemic stroke is a common type of stroke that significantly affects human well-being and quality of life. In order to further characterize the pathophysiology of ischemic stroke and develop new treatment strategies, ischemic stroke models with controllable and consistent response to potential clinical treatments are urgently needed. The middle cerebral artery occlusion (MCAO) model is currently the most widely used animal model of ischemic stroke. This review discusses various methods for constructing the MCAO model and compares their advantages and disadvantages in order to provide better approaches for studying ischemic stroke. |
Databáze: | Directory of Open Access Journals |
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