A comparison of definitions of contrast-induced nephropathy in patients with normal serum creatinine

Autor: Mohammad Reza Khatami, Nasrin Nikravan, Mojtaba Salari-Far, Safieh Davoudi, Mohammad Reza Pahlavan-Sabbagh
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Saudi Journal of Kidney Diseases and Transplantation, Vol 27, Iss 1, Pp 94-100 (2016)
Druh dokumentu: article
ISSN: 1319-2442
DOI: 10.4103/1319-2442.174086
Popis: Contrast-induced nephropathy (CIN) is the third leading cause of acute kidney injury in hospitalized patients. The prevalence of CIN is reported to range from 0% to 50%, depending not only on patient condition and the procedure used but also the definition of CIN applied. We aimed to determine the best diagnostic indicator of CIN in patients with normal serum creatinine. This study included 206 patients with normal serum creatinine who underwent coronary angiography/angioplasty. Serum creatinine level and glomerular filtration rate (GFR) were measured before and on the second and fifth days after contrast administration. The incidence of CIN based on a 25% increase in serum creatinine was calculated and compared with the incidence based on a 25% decrease in GFR or an increase of at least 0.5 mg/dL in serum creatinine. Of 206 patients, 127 were male (61.7%) and 79 were female (38.3%); the mean age was 59.56 ± 10.3 years. The prevalence of CIN was 30% based on a 25% increase in serum creatinine, 23% based on a 25% decrease in GFR (P
Databáze: Directory of Open Access Journals