Shikonin alleviates asthma phenotypes in mice via an airway epithelial STAT3-dependent mechanism

Autor: Zhang Yao, Chen Lizhan, Ouyang Haifeng
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Open Medicine, Vol 19, Iss 1, Pp 17-35 (2024)
Druh dokumentu: article
ISSN: 2391-5463
DOI: 10.1515/med-2024-1016
Popis: Asthma is an inflammatory disease where the balance between Th1/Th2 and Th17/Treg plays a crucial role in its pathogenesis. Shikonin is used to treat a variety of autoimmune diseases due to its good anti-inflammatory activity. However, the effect and mechanism of shikonin on asthma remain unknown.
Databáze: Directory of Open Access Journals