The clinical value of regional lymphadenectomy for intrahepatic cholangiocarcinoma

Autor: Facai Yang, Changkang Wu, Zhiyuan Bo, Jian Xu, Bin Yi, Jingdong Li, Yinghe Qiu
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Asian Journal of Surgery, Vol 45, Iss 1, Pp 376-380 (2022)
Druh dokumentu: article
ISSN: 1015-9584
DOI: 10.1016/j.asjsur.2021.06.031
Popis: Objective: The aim of this study was to explore the clinical value of lymph node dissection (LND) for intrahepatic cholangiocarcinoma (ICC). Methods: Clinical and pathological data were collected from 147 ICC patients who attended two tertiary centers over the past 5 years. The patients were classified into two groups: the LND group (group A) and the no-performance LND (NLND) group (group B). Clinical and pathological parameters were compared between the two groups to analyze the impact of LND on the long-term survival time of ICC patients. Results: Of the 147 patients, 54.4% (80) received LND and 42.5% (34/80) of these were found to have lymph node metastasis (LNM). LND did not increase postoperative complications (27.5%, P = 0.354), but postoperative hospital stays were longer (12.2 ± 6.3 d, P = 0.005) in group A compared with group B (20.9%, 9.5 ± 3.5 d). The 5-year survival rates of groups A and B are almost similar (21% vs 29%, P = 0.905). The overall survival rate of cN0 (diagnosis obtained by imaging) is better than pN1 (diagnosis obtained by histopathology), but lower than pN0 (all P
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