| Autor: |
Nidaa A. Ababneh, Ban Al-Kurdi, Dema Ali, Raghda Barham, Nour Sharar, Mairvat M. Mrahleh, Bareqa Salah, Abdalla Awidi |
| Jazyk: |
angličtina |
| Rok vydání: |
2020 |
| Předmět: |
|
| Zdroj: |
Stem Cell Research, Vol 48, Iss , Pp 101923- (2020) |
| Druh dokumentu: |
article |
| ISSN: |
1873-5061 |
| DOI: |
10.1016/j.scr.2020.101923 |
| Popis: |
Human induced pluripotent stem cell line (JUCTCi011-A) was generated from skin fibroblasts obtained from a 34-year-old healthy male subject from Jordan. The generated iPSCs showed typical embryonic-like characteristics. They retained their normal karyotype similar to their parental dermal fibroblast cells, expressed pluripotency markers and showed a differentiation potential into three germ layers as demonstrated by immunostaining and flow cytometry. This generated cell line can be used in disease modeling studies, to serve as a healthy control line and to help in developing novel therapeutic strategies for patients with hereditary neuromuscular diseases. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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