Immune Thrombocytopenia Associated with Hepatitis B Virus and Autoimmune Hepatitis and Recovery of Platelet Count following Liver Transplantation

Autor: Chloe Nobuhara, Diana M. Cardona, Murat O. Arcasoy, Carl L. Berg, Andrew S. Barbas
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Case Reports in Transplantation, Vol 2021 (2021)
Druh dokumentu: article
ISSN: 2090-6943
2090-6951
DOI: 10.1155/2021/8484106
Popis: Immune thrombocytopenia is a consumptive coagulopathy that can be either idiopathic or associated with infectious or autoimmune etiologies. Here, we present a case of immune thrombocytopenia in the setting of acute liver failure due to coexisting diagnoses of hepatitis B virus and autoimmune hepatitis. Our patient underwent orthotopic liver transplantation and recovered hemostatic platelet counts after treatment with romiplostim, a thrombopoietin receptor agonist, 51 days after transplantation. To our knowledge, this is the first case report of immune thrombocytopenia secondary to both hepatitis B virus and autoimmune hepatitis in a patient with acute liver failure.
Databáze: Directory of Open Access Journals
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