Association of cardiovascular complications with circulating levels of tribbles 3 human homolog and matrix metalloproteinases in Indian type 2 diabetic patients, with or without hypertension

Autor: Prashant Shirish Ratnaparkhi, Namrata B Kulkarni, Meghana U Ganu, Sanjay G Godbole, Sudha Shrikant Deo
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Zdroj: Journal of Diabetology, Vol 9, Iss 1, Pp 25-31 (2018)
Druh dokumentu: article
ISSN: 2078-7685
DOI: 10.4103/jod.jod_29_17
Popis: Aim and Objective: Matrix metalloproteinases (MMPs) and Tribbles 3 (Trb3) human homologue have been reported to induce atherosclerosis. We wanted to evaluate the association of circulating levels of Trb3 human homologue and MMPs (MMP2 and MMP9), with possible cardiovascular complications in Indian type 2 diabetic patients (type 2 diabetes mellitus [T2DM]), with or without hypertension (HT). Materials and Methods: Serum from 144 individuals, classified as follows: Group A1= (DM + HT); T2DM> 5 years + HT (n = 55); Group A2 = DM; T2DM
Databáze: Directory of Open Access Journals