Effective use of intensive treatment against multiple myeloma of recipient origin after allogeneic transplantation for acute myeloid leukemia

Autor: Félicité de Charry, Johanna Konopacki, Sarah Bugier, Vincent Foissaud, Ivan Sloma, Jean-Valère Malfuson, Pierre Arnautou
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Leukemia Research Reports, Vol 19, Iss , Pp 100366- (2023)
Druh dokumentu: article
ISSN: 2213-0489
DOI: 10.1016/j.lrr.2023.100366
Popis: We describe here a 56-years –old woman cured in our institution for an acute myeloid leukemia (AML) and a monoclonal gammopathy of undetermined significance (MGUS). In order to treat AML, underwent allogeneic stem cell transplantation in second complete remission. Four years after transplant, MGUS evolved to multiple myeloma and was intensively treated with “autologous” transplant after successful mobilization. This report illustrates: (i) a lack of efficacy of graft versus myeloma effect in a patient probably cured of AML by graft versus leukaemia effect; (ii) the ability to mobilize peripheral blood stem cells in order to perform “autologous” transplantation after allogeneic transplantation.
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