| Autor: |
Samuel Eastman, Ting Jiang, Kaeli Ficco, Chao Liao, Britley Jones, Sarina Wen, Yvette Olivas Biddle, Aya Eyceoz, Ilya Yatsishin, Todd A. Naumann, Jonathan M. Conway |
| Jazyk: |
angličtina |
| Rok vydání: |
2024 |
| Předmět: |
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| Zdroj: |
Cell Reports, Vol 43, Iss 12, Pp 115063- (2024) |
| Druh dokumentu: |
article |
| ISSN: |
2211-1247 |
| DOI: |
10.1016/j.celrep.2024.115063 |
| Popis: |
Summary: Plant roots grow in association with a community of microorganisms collectively known as the rhizosphere microbiome. Immune activation in response to elicitors like the flagellin-derived epitope flg22 restricts bacteria on plant roots but also inhibits plant growth. Some commensal root-associated bacteria are capable of suppressing the plant immune response to elicitors. In this study, we investigated the ability of 165 root-associated bacteria to suppress flg22-induced immune activation and growth restriction. We demonstrate that a type II secreted subtilase, which we term immunosuppressive subtilase A (IssA), from Dyella japonica strain MF79 cleaves the immune elicitor peptide flg22 and suppresses immune activation. IssA homologs are found in other plant-associated commensals, with particularly high conservation in the order Xanthomonadales. This represents a novel mechanism by which commensal microbes modulate flg22-induced immunity in the rhizosphere microbiome. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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