Immunohistochemical expression of TGF-β1 and MMP-9 in periapical lesions
| Autor: | Pâmella Recco ÁLVARES, José Alcides Almeida de ARRUDA, Leorik Pereira da SILVA, George João Ferreira do NASCIMENTO, Maria Fonseca da SILVEIRA, Ana Paula Veras SOBRAL |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: | |
| Zdroj: | Brazilian Oral Research, Vol 31, Iss 0 (2017) |
| Druh dokumentu: | article |
| ISSN: | 1807-3107 70068194 |
| DOI: | 10.1590/1807-3107bor-2017.vol31.0051 |
| Popis: | Abstract The objective of this study was to evaluate the expression of matrix metalloproteinase 9 (MMP-9) and transforming growth factor beta (TGF-β1) in periapical lesion samples correlated with the intensity of the inflammatory infiltrate and thickness of the epithelial lining. Forty-five cases of periapical lesions (23 periapical granulomas and 22 radicular cysts) were subjected to morphological and immunohistochemical analyses using anti-MMP-9 and anti-TGF-β1 antibodies. The data were analyzed using the following tests: non-parametric Mann-Whitney, chi-square, Fisher’s exact test and Spearman’s correlation test (P |
| Databáze: | Directory of Open Access Journals |
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