| Autor: |
Qing Li, Xiao-Xin Zhang, Li-Peng Hu, Bo Ni, Dong-Xue Li, Xu Wang, Shu-Heng Jiang, Hui Li, Min-Wei Yang, Yong-Sheng Jiang, Chun-Jie Xu, Xue-Li Zhang, Yan-Li Zhang, Pei-Qi Huang, Qin Yang, Yang Zhou, Jian-ren Gu, Gary Gui-Shan Xiao, Yong-wei Sun, Jun Li, Zhi-Gang Zhang |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
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| Zdroj: |
Nature Communications, Vol 14, Iss 1, Pp 1-19 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-023-36521-0 |
| Popis: |
Pancreatic ductal adenocarcinoma (PDAC) cells can utilise the tumour microenvironment to metastasise to the liver. Here the authors show that hepatoctyes overexpress SLIT2 to enable premetastatic niche formation for ROBO1-positive PDAC cells to support the survival of these tumour cells in the liver. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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