Antiparasitic treatment with itraconazole and amiodarone in 2 dogs with severe, symptomatic Chagas cardiomyopathy
Autor: | Elizabeth L. Malcolm, Ashley B. Saunders, Jordan P. Vitt, Bruno G. Boutet, Sarah A. Hamer |
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Jazyk: | angličtina |
Rok vydání: | 2022 |
Předmět: | |
Zdroj: | Journal of Veterinary Internal Medicine, Vol 36, Iss 3, Pp 1100-1105 (2022) |
Druh dokumentu: | article |
ISSN: | 1939-1676 0891-6640 |
DOI: | 10.1111/jvim.16422 |
Popis: | Abstract Chagas cardiomyopathy, caused by the protozoal parasite Trypanosoma cruzi, is characterized by arrhythmias, myocardial damage, heart failure, and sudden death. We describe 2 dogs with severe, symptomatic Chagas cardiomyopathy characterized by myocardial dysfunction and electrocardiographic abnormalities that were managed with a combination of cardiac medications and antiparasitic treatment with itraconazole and amiodarone. Both dogs died suddenly within 6 months of diagnosis. These cases highlight the need for early detection of Chagas disease in dogs and continued research to develop effective antiparasitic treatment protocols. |
Databáze: | Directory of Open Access Journals |
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