Acute Kidney Injury Definition and In‐Hospital Mortality in Patients Undergoing Primary Percutaneous Coronary Intervention for ST‐Segment Elevation Myocardial Infarction

Autor: Giancarlo Marenzi, Nicola Cosentino, Marco Moltrasio, Mara Rubino, Gabriele Crimi, Stefano Buratti, Marco Grazi, Valentina Milazzo, Alberto Somaschini, Rita Camporotondo, Stefano Cornara, Monica De Metrio, Alice Bonomi, Fabrizio Veglia, Gaetano M. De Ferrari, Antonio L. Bartorelli
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 5, Iss 7 (2016)
Druh dokumentu: article
ISSN: 2047-9980
DOI: 10.1161/JAHA.116.003522
Popis: BackgroundAcute kidney injury (AKI) has been associated with increased mortality in ST‐segment elevation myocardial infarction. We compared the mortality predictive accuracy of the 3 AKI definitions used most widely for patients with ST‐segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. Methods and ResultsWe included 3771 patients with ST‐segment elevation myocardial infarction treated with primary percutaneous coronary intervention at 2 Italian hospitals. AKI incidence was evaluated according to creatinine increases of ≥25% (AKI‐25), ≥0.3 mg/dL (AKI‐0.3), and ≥0.5 mg/dL (AKI‐0.5). The primary end point was in‐hospital mortality. Overall, 557 (15%), 522 (14%), and 270 (7%) patients developed AKI‐25, AKI‐0.3, and AKI‐0.5, respectively (P
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