| Autor: |
Tong Xiang, Yu-Xin Lin, Wenlong Ma, Hao-Jiong Zhang, Ke-Ming Chen, Gui-Ping He, Xiao Zhang, Miao Xu, Qi-Sheng Feng, Ming-Yuan Chen, Mu-Sheng Zeng, Yi-Xin Zeng, Lin Feng |
| Jazyk: |
angličtina |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018) |
| Druh dokumentu: |
article |
| ISSN: |
2041-1723 |
| DOI: |
10.1038/s41467-018-07308-5 |
| Popis: |
EBV latent infection contributes to the pathogenesis of epithelial malignancies by inducing angiogenesis. Here, the authors show EBV promotes vasculogenic mimicry in EBV associated epithelial cancers via AKT/HIF-1α pathway and combination therapy of HIF-1α and VEGF reduces tumour growth. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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