Eosinophilic Cationic Protein and Immunoglobulin E: Unraveling Biomarkers in Chronic Pediatric Cough

Autor: Snezhina Lazova, Kremena Naydenova, Tsvetelina Velikova
Jazyk: angličtina
Rok vydání: 2024
Předmět:
Zdroj: Sinusitis, Vol 8, Iss 1, Pp 1-10 (2024)
Druh dokumentu: article
ISSN: 2673-351X
DOI: 10.3390/sinusitis8010001
Popis: Although the cough reflex is one of the essential protective mechanisms in the respiratory tract, it is considered a considerable health problem in adults and children when it becomes chronic and hypersensitive. However, the need for biomarkers for chronic cough in children and adults is critical. The problem with cough is also a severe symptom in hypersensitivity children. Respiratory infections are a considerable challenge for pediatricians, especially in allergic children. The term cough hypersensitivity syndrome, although introduced in adults, was questioned for children. Eosinophil cationic protein (ECP) is a promising marker for chronic cough but still needs to be validated and proved in clinical settings. In this review article, we aimed to discuss the possible role of ECP in connection to IgE for chronic cough in children.
Databáze: Directory of Open Access Journals
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