Incidence, Clinicopathological Profile and Location - Based Outcome of Intracranial Meningiomas: 10-Year Institutional Study with Review of Literature

Autor: Feroze Ganai, Humam Nisar Tanki, Afaq Sherwani, Kirmani Altaf, Nazish Chisti, Altaf Ramzan
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Indian Journal of Neurosurgery, Vol 10, Iss 01, Pp 042-048 (2021)
Druh dokumentu: article
ISSN: 2277-954X
2277-9167
0040-1714
DOI: 10.1055/s-0040-1714436
Popis: Intracranial meningiomas are the most common extra-axial tumors, representing 15% of all brain tumors. Arising from the arachnoid cells, and common in middle-aged women, 90% meningiomas are benign. We conducted a 10-year study on 183 cases of intracranial meningiomas and observed a lower and decreasing trend; the mean age was 43.3 years but there was also a significant incidence in young females. Parasagittal/falx (29%), sphenoid ridge, convexity meningiomas and middle cranial fossa locations were more common. Histopathologically, meningothelial meningioma was the most common. Benign (WHO I) tumors were found in above 90%, atypical (WHO II) in 5% cases, and malignant (WHO III) in < 4% patients. Most patients underwent Simpsons Grade I excision (35.6%) with dural reconstruction because of late presentations. Posterior fossa meningiomas were mostly benign, while intraventricular ones were mostly malignant with highest postoperation mortality. Mortality in operated patients was 9.8% but was highest in anterior fossa tumors (12.5%).
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