BLOOD CONTENTS OF DEFENSINS IN PATIENTS WITH PNEUMONIAS CAUSED BY INFLUENZA А/H1N1
| Autor: | E. N. Romanova, A. V. Govorin, V. V. Gorbunov, S. A. Lukyanov |
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| Jazyk: | ruština |
| Rok vydání: | 2014 |
| Předmět: | |
| Zdroj: | Медицинская иммунология, Vol 14, Iss 3, Pp 239-242 (2014) |
| Druh dokumentu: | article |
| ISSN: | 1563-0625 2313-741X |
| DOI: | 10.15789/1563-0625-2012-3-239-242 |
| Popis: | Abstract. Defensin amounts in severe forms of influenza-associated pneumonia and acute respiratory distresssyndrome is increased to a lesser degree than in pneumonias with milder clinical course. This difference may be determined by selective accumulation of defensins in areas of infectious lesions. Mean content of α-defensins in non-severe pneumonias with influenza А/H1N1 accompanied by normocytosis or leukopenia, is higher than in bacterial pneumonias with leukocytosis. High levels of defensins, along with substantially increased neutrophil counts, associated with normocytosis or leukopenia, reflect a pronounced systemic inflammatory response caused by influenza А/H1N1. |
| Databáze: | Directory of Open Access Journals |
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