The Oligodendrocyte Transcription Factor 2 OLIG2 regulates transcriptional repression during myelinogenesis in rodents

Autor: Kunkun Zhang, Shaoxuan Chen, Qihua Yang, Shuanghui Guo, Qiang Chen, Zhixiong Liu, Li Li, Mengyun Jiang, Hongda Li, Jin Hu, Xu Pan, Wenbo Deng, Naian Xiao, Bo Wang, Zhan-xiang Wang, Liang Zhang, Wei Mo
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/s41467-022-29068-z
Popis: Transcription factors regulate gene programs during myelination. Here, the authors show that the Oligodendrocyte Transcription Factor 2 (OLIG2) regulates the differentiation of oligodendrocyte progenitor cells into immature oligodendrocytes via SETDB1 during myelination and remyelination in rodents.
Databáze: Directory of Open Access Journals