| Autor: |
Youbin Xiang, Dai Tsuchiya, Fengli Guo, Jennifer Gardner, Scott McCroskey, Andrew Price, Eelco C Tromer, James R Walters, Cathleen M Lake, R Scott Hawley |
| Jazyk: |
angličtina |
| Rok vydání: |
2023 |
| Předmět: |
|
| Zdroj: |
G3: Genes, Genomes, Genetics, Vol 13, Iss 5 (2023) |
| Druh dokumentu: |
article |
| ISSN: |
2160-1836 |
| DOI: |
10.1093/g3journal/jkad058 |
| Popis: |
AbstractMeiosis is usually described as 4 essential and sequential processes: (1) homolog pairing; (2) synapsis, mediated by the synaptonemal complex; (3) crossing over; and (4) segregation. In this canonical model, the maturation of crossovers into chiasmata plays a vital role in holding homologs together and ensuring their segregation at the first meiotic division. However, Lepidoptera (moths and butterflies) undergo 3 distinct meiotic processes, only one of which is canonical. Lepidoptera males utilize 2 meiotic processes: canonical meiosis that produces nucleated fertile sperm, and a noncanonical meiosis that produces anucleated nonfertile sperm which are nonetheless essential for reproduction. Lepidoptera females, which carry heteromorphic sex chromosomes, undergo a completely achiasmate (lacking crossovers) meiosis, thereby requiring an alternative mechanism to ensure proper homolog segregation. Here, we report that the development of a molecular cell biology toolkit designed to properly analyze features of meiosis, including the synaptonemal complex structure and function, in the silkworm Bombyx mori.BombyxBombyx |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
|
