Clinical and magnetic resonance study of a case of subacute sclerosing panencephalitis treated with ketogenic diet

Autor: Gian Luigi Gigli, Mariarosaria Valente, Ilaria Del Negro, Daniele Bagatto, Riccardo Garbo, Christian Lettieri, Andrea Bernardini, Annacarmen Nilo, Maria Rosaria Peri, Davide Pecori
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: BMJ Neurology Open, Vol 3, Iss 2 (2021)
Druh dokumentu: article
ISSN: 2632-6140
DOI: 10.1136/bmjno-2021-000176
Popis: Background Subacute sclerosing panencephalitis is a progressive neurodegenerative disorder caused by a latent and mutant measles virus which is extremely rare in developed countries. The lack of effective treatments leads to the research of other anti-inflammatory and neuroprotective treatments.Case Here we present a case of a 17-year-old patient affected by subacute sclerosing panencephalitis who manifest a dramatic improvement in neurological and general clinical conditions, as well as an arrest in the progression of demyelinating process in the central nervous system, after the beginning of a high ratio ketogenic diet.Conclusions Given its anti-inflammatory, antioxidant and metabolic effects, we believe that ketogenic diet utilisation could be a rational approach, can be considered a safe add-on therapy, carrying on with only a minimal risk of adverse effects or interactions.
Databáze: Directory of Open Access Journals