| Autor: |
Sang Joon Son, Bumhee Park, Jin Wook Choi, Hyun Woong Roh, Na-Rae Kim, Jae Eun Sin, Haena Kim, Hyun Kook Lim, Chang Hyung Hong |
| Jazyk: |
angličtina |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Frontiers in Psychiatry, Vol 10 (2019) |
| Druh dokumentu: |
article |
| ISSN: |
1664-0640 |
| DOI: |
10.3389/fpsyt.2019.00615 |
| Popis: |
Background: It has been suggested that maintaining the efficient organization of the brain’s functional connectivity (FC) supports neuroflexibility under neurogenerative stress. This study examined psychological resilience-related FC in 112 older adults with mild cognitive impairment (MCI).Methods: Using a resting-state functional magnetic resonance imaging (fMRI) approach, we investigated reorganization of the orbitofrontal gyrus (OFG)/amygdala (AMG)/hippocampus (HP)/parahippocampal gyrus (PHG) FC according to the different levels of resilience scale.Results: Compared with the low resilient group, the high resilient group had greater connectivity strengths between the left inferior OFG and right superior OFG (P < 0.05, Bonferroni corrected), between the right inferior OFG and left PHG (P < 0.05, Bonferroni corrected), and between the right middle OFG and left PHG (false discovery rate < 0.05).Conclusion: Psychological resilience may be associated with enhancement of the orbitofrontal network in the elderly with MCI. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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