Association between triglyceride glucose index and risk of cancer: A meta-analysis

Autor: Huan Wang, Feifei Yan, Yani Cui, Feinan Chen, Guixia Wang, Weiwei Cui
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Frontiers in Endocrinology, Vol 13 (2023)
Druh dokumentu: article
ISSN: 1664-2392
DOI: 10.3389/fendo.2022.1098492
Popis: BackgroundTriglyceride glucose (TyG) index as a more convenient and reliable predictor of insulin resistance (IR) is thought to be associated with many diseases, but its relationship with cancer remains unclear.MethodsThe meta-analysis was conducted to evaluate the effects of TyG index on cancer risk utilizing the available evidence. PubMed, EMBASE, Medline, Cochrane Library and Web of Science were searched from their inception up to July 2022. A random-effects model was used to calculate the effect estimates and 95% confidence intervals (CIs).ResultsA total of 6 observational studies met our inclusion criteria, which including 992292 participants. The meta-analysis indicated that the higher TyG index increased cancer risk compared to the lower TyG index group (total effect size =1.14, 95% CI [1.08, 1.20], P
Databáze: Directory of Open Access Journals