Role of multiparametric magnetic resonance imaging in the diagnosis and staging of urinary bladder cancer
| Autor: | Essam A. Shalaby, Ahmed R. Mohamed, Tarek H. Elkammash, Rasha T. Abouelkheir, Ahmed M. Housseini |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Current Urology, Vol 16, Iss 3, Pp 127-135 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1661-7649 00000000 |
| DOI: | 10.1097/CU9.0000000000000128 |
| Popis: | Abstract. Objectives. To assess the role of multiparametric magnetic resonance imaging (mp-MRI) in the diagnosis and staging of urinary bladder cancer (BC). Materials and methods. Fifty patients diagnosed with bladder masses underwent mp-MRI study. The results of 3 image sets were analyzed and compared with the histopathological results as a reference standard: T2-weighted image (T2WI) plus dynamic contrast-enhanced (DCE), T2WI plus diffusion-weighted images (DWI), and mp-MRI, including T2WI plus DWI and DCE. The diagnostic accuracy of mp-MRI was evaluated using receiver operating characteristic curve analysis. Results. The accuracy of T2WI plus DCE for detecting muscle invasion of BC was 79.5% with a fair agreement with histopathological examination (κ = 0.59); this percentage increased up to 88.6% using T2WI plus DWI, with good agreement with histopathological examination (κ = 0.74), whereas mp-MRI had the highest overall accuracy (95.4%) and excellent agreement with histopathological data (κ = 0.83). Multiparametric MRI can differentiate between low- and high-grade bladder tumors with a high sensitivity and specificity of 93.3% and 98.3%, respectively. Conclusions. Multiparametric MRI is an acceptable method for the preoperative detection and accurate staging of BC, with reasonable accuracy in differentiating between low- and high-grade BC. |
| Databáze: | Directory of Open Access Journals |
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