Comparison between surgery and thermal ablation for adrenal metastases: a retrospective study
| Autor: | Lin Xie, Han Qi, Fei Cao, Lujun Shen, Shuanggang Chen, Ying Wu, Tao Huang, Ze Song, Weijun Fan |
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| Jazyk: | angličtina |
| Rok vydání: | 2021 |
| Předmět: | |
| Zdroj: | International Journal of Hyperthermia, Vol 38, Iss 1, Pp 1541-1547 (2021) |
| Druh dokumentu: | article |
| ISSN: | 0265-6736 1464-5157 02656736 |
| DOI: | 10.1080/02656736.2021.1993356 |
| Popis: | Purpose To retrospectively compare the efficacy and safety of surgical resection (SR) and thermal ablation for the treatment of adrenal metastases. Methods From January 2008 to December 2018, 133 patients with adrenal metastases who underwent SR (n = 76) or thermal ablation (n = 57) were enrolled. The mean tumor size was 58.00 ± 10.65 mm (22-80 mm) in the SR group and 58.03 ± 12.76 mm (34–89 mm) in the thermal ablation group. Local progression-free survival (LPFS) and safety were compared between the two groups using the Kaplan–Meier method and log-rank tests. Cox proportional hazard regression models were used to evaluate the prognostic factors of LPFS. Complications, hospitalization days, and blood loss were also assessed. Results The median follow-up was 29.0 months (range, 20.4–37.6 months). No treatment-related mortality was observed. The 1-, 3- and 5-year LPFS rates were 74.0%, 62.8%, and 31.4% in the SR group and 72.8%, 68.7%, and 51.5% in the ablation group, with the median LPFS of 41.5 months (95% CI: 9.3–23.4 months) vs. 47.9 months (95% CI 20.6–75.8 months), respectively (p = 0.784). Tumor size ≥3 cm was the only significant risk factor for LPFS (p = 0.031). The ablation group was superior to the SR group with a lower major complication rate (4.1% vs. 14.5%, p = 0.03), less blood loss (1 ml vs. 100 ml, p |
| Databáze: | Directory of Open Access Journals |
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