Hemophilia A - acquired during coronary artery bypass grafting
| Autor: | Akintorin Abayomi, Alexander Bozana, Leila Ahmad Abou, Humanez Jose, Mcpencow James |
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| Jazyk: | English<br />Serbian |
| Rok vydání: | 2013 |
| Předmět: | |
| Zdroj: | Scripta Medica, Vol 44, Iss 2, Pp 90-91 (2013) |
| Druh dokumentu: | article |
| ISSN: | 2490-3329 2303-7954 |
| Popis: | We report a challenging case of a rare cause of post operative bleeding that occurred after the coronary artery by-pass graft procedure. We believe that acquired hemophilia A was the main culprit. Patient post CABG developed nonsurgical bleeding with new isolated PTT prolongation. Bleeding was resistant to conventional therapy. Mixing studies didn't correct PTT, thus we ruled out factor deficiencies. Heparin effect was excluded by normal factor X levels. Patient received factor VIII inhibitor bypass therapy after which corrected PTT and stopped bleeding. The triad of acquired coagulopathy, noncorrectable PTT, and exclusion of heparin effect, make acquired hemophilia A the most likely diagnosis. |
| Databáze: | Directory of Open Access Journals |
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