Autor: |
Belinda J Gabbe, Rinaldo Bellomo, Terence J O'Brien, Andrew Chow, Anthony Delaney, Michael Reade, Anthony Trapani, Andrew Udy, Melinda Fitzgerald, James Anstey, David Bowen, D James Cooper, Judith Bellapart, Toby Jeffcote, Camila R Battistuzzo, Mark P Plummer, Robert McNamara, Rebecca Roach, Torgeir Westerlund, Shailesh Bihari, Mark Weeden, Rosalind L Jeffree, Alistair D Nichol |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
|
Zdroj: |
BMJ Open, Vol 14, Iss 2 (2024) |
Druh dokumentu: |
article |
ISSN: |
2044-6055 |
DOI: |
10.1136/bmjopen-2023-080614 |
Popis: |
Introduction Traumatic brain injury (TBI) is a heterogeneous condition in terms of pathophysiology and clinical course. Outcomes from moderate to severe TBI (msTBI) remain poor despite concerted research efforts. The heterogeneity of clinical management represents a barrier to progress in this area. PRECISION-TBI is a prospective, observational, cohort study that will establish a clinical research network across major neurotrauma centres in Australia. This network will enable the ongoing collection of injury and clinical management data from patients with msTBI, to quantify variations in processes of care between sites. It will also pilot high-frequency data collection and analysis techniques, novel clinical interventions, and comparative effectiveness methodology.Methods and analysis PRECISION-TBI will initially enrol 300 patients with msTBI with Glasgow Coma Scale (GCS) |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|