Integrated Network Analysis and Effective Tools in Plant Systems Biology

Autor: Atsushi eFukushima, Shigehiko eKanaya, Kozo eNishida
Jazyk: angličtina
Rok vydání: 2014
Předmět:
Zdroj: Frontiers in Plant Science, Vol 5 (2014)
Druh dokumentu: article
ISSN: 1664-462X
DOI: 10.3389/fpls.2014.00598
Popis: One of the ultimate goals in plant systems biology is to elucidate the genotype-phenotype relationship in plant cellular systems. Integrated network analysis that combines omics data with mathematical models has received particular attention. Here we focus on the latest cutting-edge computational advances that facilitate their combination. We highlight (1) network visualization tools, (2) pathway analyses, (3) genome-scale metabolic reconstruction, and (4) the integration of high-throughput experimental data and mathematical models. Multi-omics data that contain the genome, transcriptome, proteome, and metabolome and mathematical models are expected to integrate and expand our knowledge of complex plant metabolisms.
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