Outcomes of varicose vein surgery in patients with HIV/AIDS – a nested case-control study

Autor: António Pereira-Neves, Diogo Domingues-Monteiro, Leandro Nóbrega, Luís Duarte-Gamas, Alfredo Cerqueira, João Rocha-Neves, José Oliveira-Pinto, Armando Mansilha
Jazyk: portugalština
Rok vydání: 2023
Předmět:
Zdroj: Angiologia e Cirurgia Vascular, Vol 18, Iss 4 (2023)
Druh dokumentu: article
ISSN: 1646-706X
2183-0096
DOI: 10.48750/acv.492
Popis: INTRODUCTION: Currently, people living with HIV/ AIDS (PLWHA) attain a life expectancy similar to a non-HIV population. However, these patients experience a status of chronic inflammation, which is a known cause of arteriopathy. Yet, literature is scarce regarding the potential venous inflammatory effect, especially after varicose vein surgery. The aim of this study was to perform a descriptive analysis alongside evaluating short and long- term outcomes after varicose vein surgery in PLWHA while comparing with a control group. METHODS: A retrospective nested case-control study was performed resorting to codification. All PLWHA patients which had any hospital interaction with the Vascular Surgery Department (either outpatient clinic, emergency or surgery) due to venous disease between April 2006 and December 2019 were identified. PLWHA found to have undergone varicose vein surgery within the study inclusion period were included. The immediately consecutive varicose vein surgery in a patient with no-HIV infection was included in the control group in a 1:1 ratio. Comorbidities were collected at the time of index event. RESULTS: The cohort included 118 patients (59 PLWHA and 59 control) and had a mean follow-up of 86 [Interquartile range (IQR) 25-75%, 43-111] months. At baseline, PLWHA were younger (45.2 ± 10.71 vs 49.9 ± 10.69 years, p=0.017) and had a male predominance (54% vs 27%, p=0.003). Furthermore, there were a higher prevalence of smokers (54% vs 17%, p
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