Antifungal Effect of Chitosan as Ca²⁺ Channel Blocker
| Autor: | Choon Geun Lee, Ja Choon Koo, Jae Kweon Park |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | The Plant Pathology Journal, Vol 32, Iss 3, Pp 242-250 (2016) |
| Druh dokumentu: | article |
| ISSN: | 1598-2254 46643842 |
| DOI: | 10.5423/PPJ.OA.08.2015.0162 |
| Popis: | The aim of this study was to investigate antifungal activity of a range of different molecular weight (MW) chitosan against Penicillium italicum. Our results demonstrate that the antifungal activity was dependent both the MW and concentration of the chitosan. Among a series of chitosan derived from the hydrolysis of high MW chitosan, the fractions containing various sizes of chitosan ranging from 3 to 15 glucosamine units named as chitooligomers-F2 (CO-F2) was found to show the highest antifungal activity against P. italicum. Furthermore, the effect of CO-F2 toward this fungus was significantly reduced in the presence of Ca²⁺, whereas its effect was recovered by ethylenediaminetetraacetic acid, suggesting that the CO-F2 acts via disruption of Ca²⁺ gradient required for survival of the fungus. Our results suggest that CO-F2 may serve as potential compounds to develop alternatives to synthetic fungicides for the control of the postharvest diseases. |
| Databáze: | Directory of Open Access Journals |
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