Association of Moderate Beer Consumption with the Gut Microbiota and SCFA of Healthy Adults

Autor: Natalia González-Zancada, Noemí Redondo-Useros, Ligia E. Díaz, Sonia Gómez-Martínez, Ascensión Marcos, Esther Nova
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Molecules, Vol 25, Iss 20, p 4772 (2020)
Druh dokumentu: article
ISSN: 1420-3049
DOI: 10.3390/molecules25204772
Popis: Fermented alcoholic drinks’ contribution to the gut microbiota composition is mostly unknown. However, intestinal microorganisms can use compounds present in beer. This work explored the associations between moderate consumption of beer, microbiota composition, and short chain fatty acid (SCFA) profile. Seventy eight subjects were selected from a 261 healthy adult cohort on the basis of their alcohol consumption pattern. Two groups were compared: (1) abstainers or occasional consumption (ABS) (n = 44; n = 34; 200 to 600 mL 5% vol. beer/day; Clostridiaceae was lower (p = 0.009), while Blautia and Pseudobutyrivibrio were higher (p = 0.044 and p = 0.037, respectively) in BEER versus ABS. In addition, Alkaliphilus, in men, showed lower abundance in BEER than in ABS (p = 0.025). Butyric acid was higher in BEER than in ABS (p = 0.032), and correlated with Pseudobutyrivibrio abundance. In conclusion, the changes observed in a few taxa, and the higher butyric acid concentration in consumers versus non-consumers of beer, suggest a potentially beneficial effect of moderate beer consumption on intestinal health.
Databáze: Directory of Open Access Journals
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