| Autor: |
Gabriel Velez, C. Nathaniel Roybal, Elaine Binkley, Alexander G. Bassuk, Stephen H. Tsang, Vinit B. Mahajan |
| Jazyk: |
angličtina |
| Rok vydání: |
2017 |
| Předmět: |
|
| Zdroj: |
American Journal of Ophthalmology Case Reports, Vol 5, Iss C, Pp 107-110 (2017) |
| Druh dokumentu: |
article |
| ISSN: |
2451-9936 |
| DOI: |
10.1016/j.ajoc.2016.12.023 |
| Popis: |
Purpose: To report a case of elevated intraocular pressure with retinal detachment. Observations: Liquid chromatography and tandem mass spectrometry was performed on the patient aqueous biopsy. Protein levels were analyzed with 1-way analysis of variance (ANOVA) and unbiased clustering. High levels of rod outer segment proteins were not detected, suggesting that this was not a case of Schwartz-Matsuo syndrome. Instead, elevated levels of Hepcidin (HEPC) and Cystatin C (CYTC; candidate biomarkers for primary open angle glaucoma) were detected, suggesting a different, unknown etiology. Conclusions and importance: Molecular diagnoses can differentiate between clinical diagnoses and point to common biomarkers or disease mechanisms. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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