From the choice of antihypertensive drug to the choice of fixed combinations of antihypertensive drugs: a paradigm shift

Autor: O D Ostroumova, O V Bondarets, I I Kopchenov, T F Guseva
Jazyk: ruština
Rok vydání: 2015
Předmět:
Zdroj: Системные гипертензии, Vol 12, Iss 4, Pp 23-29 (2015)
Druh dokumentu: article
ISSN: 2075-082X
2542-2189
Popis: The article considers modern approaches to treatment of arterial hypertension. Emphasizes the need for combination antihypertensive therapy, mainly fixed combinations of antihypertensive drugs, patients with high and very high risk already at the start of treatment. Discusses the advantages of combinations of blockers of receptors of angiotensin II to diuretics and calcium antagonists, as well as clinical situations in which these combinations are a priority. Considered the evidence base, pharmacokinetics and clinical benefit of the representative of a class of blockers of receptors for angiotensin II and losartan.
Databáze: Directory of Open Access Journals