Association of bone mineral density with bone texture attributes extracted using routine magnetic resonance imaging

Autor: Jamilly Gomes Maciel, Iana Mizumukai de Araújo, Lucio C. Trazzi, Paulo Mazzoncini de Azevedo-Marques, Carlos Ernesto Garrido Salmon, Francisco José Albuquerque de Paula, Marcello Henrique Nogueira-Barbosa
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Clinics, Vol 75 (2020)
Druh dokumentu: article
ISSN: 1980-5322
DOI: 10.6061/clinics/2020/e1766
Popis: OBJECTIVE: Dual-energy X-ray absorptiometry (DXA)-derived bone mineral density (BMD) often fails to predict fragility fractures. Quantitative textural analysis using magnetic resonance imaging (MRI) may potentially yield useful radiomic features to predict fractures. We aimed to investigate the correlation between BMD and texture attributes (TAs) extracted from MRI scans and the interobserver reproducibility of the analysis. METHODS: Forty-nine volunteers underwent lumbar spine 1.5-T MRI and DXA. Three-dimensional (3-D) gray-level co-occurrence matrices were measured from routine sagittal T2 fast spin-echo images using the IBEX software. Twenty-two TAs were extracted from 3-D segmented L3 vertebrae. The estimated concordance coefficient was calculated using linear regression analysis. A Pearson correlation coefficient analysis was performed to evaluate the correlation between BMD and the TAs. Interobserver reproducibility was assessed with the concordance coefficient described by Lin. RESULTS: The results revealed a fair-to-moderate significant correlation between BMD and 13 TAs (r=−0.20 to 0.39; p
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