Transcriptional bursting is intrinsically caused by interplay between RNA polymerases on DNA

Autor: Keisuke Fujita, Mitsuhiro Iwaki, Toshio Yanagida
Jazyk: angličtina
Rok vydání: 2016
Předmět:
Zdroj: Nature Communications, Vol 7, Iss 1, Pp 1-10 (2016)
Druh dokumentu: article
ISSN: 2041-1723
DOI: 10.1038/ncomms13788
Popis: Transcriptional bursting is a potential source of cell-to-cell variability but the molecular mechanisms are unclear. Here the authors use single molecule imaging to analyse the kinetics of bursting on DNA and observe that bursting is an intrinsic property of RNA polymerases on DNA.
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