A Time to Pause and Reflect: When a Patient with Autoimmune Hepatitis Stops Responding to Corticosteroids
| Autor: | Lewis Tsang, Mitali Fadia, Shivakumar Chitturi |
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| Jazyk: | angličtina |
| Rok vydání: | 2016 |
| Předmět: | |
| Zdroj: | Case Reports in Gastrointestinal Medicine, Vol 2016 (2016) |
| Druh dokumentu: | article |
| ISSN: | 2090-6528 2090-6536 |
| DOI: | 10.1155/2016/7092434 |
| Popis: | Drug-induced liver injury (DILI) with features of autoimmunity (AI) is a challenging diagnosis to make particularly due to its apparent corticosteroid responsiveness. We present the case of a 74-year-old woman who presented with a 2-week history of jaundice and fatigue. She was initially diagnosed with autoimmune hepatitis (AIH) based on biochemical and histological characteristics and prompt response with budesonide but a biochemical relapse occurred soon after inadvertent rechallenge with irbesartan, a drug that she had discontinued prior to her presentation but was not initially considered to be a cause of her symptoms. |
| Databáze: | Directory of Open Access Journals |
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