Use of nebulized naloxone to reverse methadone overdose – A case report and review of literature

Autor:	Muhammad Sameed, Heidi Teague
Jazyk:	angličtina
Rok vydání:	2019
Předmět:	naloxone opioid overdose nebulized naloxone Internal medicine RC31-1245
Zdroj:	Journal of Community Hospital Internal Medicine Perspectives, Vol 9, Iss 5, Pp 422-424 (2019)
Druh dokumentu:	article
ISSN:	2000-9666 20009666
DOI:	10.1080/20009666.2019.1659664
Popis:	Opioid use is a frequent cause of morbidity and mortality in the USA. We report a case of methadone overdose reversed with naloxone nebulization. Peripheral IV access can be difficult to obtain in patients with a history of IV drug abuse making needless routes of naloxone administration useful. When naloxone is administered as a bolus, chronically opioid dependent patients are more prone to violent withdrawal symptoms. When successful, nebulized naloxone reverses intoxication and allows the patient to self-titrate the discontinuation of naloxone when they are alert enough to remove the mask. Nebulized naloxone can provide needleless and noninvasive administration for the reversal of opioid overdose.
Databáze:	Directory of Open Access Journals
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