Antidiabetic and hepato-renal protective effects of medicinal plants in STZ induced diabetic rats
| Autor: | I. Tehseen, T. U. Haq, I. Ilahi, A. A. Khan, M. Attaullah, G. Y. Zamani, S. Zaman, I. Ismail |
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| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: | |
| Zdroj: | Brazilian Journal of Biology, Vol 84 (2022) |
| Druh dokumentu: | article |
| ISSN: | 1678-4375 1519-6984 |
| DOI: | 10.1590/1519-6984.260189 |
| Popis: | Abstract The antidiabetic and hepato-renal protective effects of Citrullus colocynthis and Momordica charantia ethanol extracts were investigated in streptozotocin (STZ) induced diabetic male albino rats. Diabetic rats were treated with C. colocynthis, M. charantia or C. colocynthis + M. charantia mixed extract at a dose of 250 mg /kg body weight per oral per day for 21 days. The mean body weight of all the diabetic rat groups on day 1 of treatment (day 10 of diabetes) was significantly lower than the normal control rat group (P 200 mg/dl) than the normal control rat group (95.5 ± 2.7). At the end of treatment (day 21), the diabetic rats treated with plant extracts showed significant increase (P |
| Databáze: | Directory of Open Access Journals |
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