miRNA-23b-5p affects the proliferation, migration and invasion of osteosarcoma by targeting TMEM127

Autor:	Dan Zu, Qi Dong, Jun Yao, Sunfang Chen, Bin Fang, Jun Ma, Bing Wu
Jazyk:	angličtina
Rok vydání:	2022
Předmět:	miR-23b-5p Osteosarcoma Migration Invasion Proliferation Neoplasms. Tumors. Oncology. Including cancer and carcinogens RC254-282
Zdroj:	Discover Oncology, Vol 13, Iss 1, Pp 1-8 (2022)
Druh dokumentu:	article
ISSN:	2730-6011
DOI:	10.1007/s12672-022-00519-9
Popis:	Highlights Survival rates remain very low in patients with osteosarcoma (OS). Identification of new diagnostic biomarkers and therapeutic targets is essential. miR-23b-5p was transfected into OS cells to study the biological effects. miR-23b-5p promoted cell proliferation and metastasis in OS by targeting TMEM127. miR-23b-5p may provide diagnostic value in the treatment of OS.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0c7662a2b8764c818ae67144c26dd825 Zobrazit plný text záznamu Full text from SpringerLink View record in DOAJ