Serum thymidine kinase 1 protein concentration for predicting early progression and monitoring the response to TACE in hepatocellular carcinomas: a network meta-analysis

Autor: Hongbo Ma, Ailian Hei, Ji Zhou, Ellen He, Sven Skog, Jin Li
Jazyk: angličtina
Rok vydání: 2021
Předmět:
Zdroj: Future Science OA, Vol 7, Iss 7 (2021)
Druh dokumentu: article
ISSN: 2056-5623
84160969
DOI: 10.2144/fsoa-2021-0016
Popis: Aim: A meta-analysis was conducted to evaluate the clinical significance of serum thymidine kinase 1 protein concentration (STK1p) in distinguishing between hepatocellular carcinomas (HCC) and non-HCC for predicting early progression and monitoring the response to transarterial chemoembolization in HCC. Material & methods: A total of 24 eligible studies were included, containing 1849 HCC patients and 1069 healthy subjects. Results: The STK1p level significantly increased from normal controls to benign/pre-HCC and HCC (p
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