Biochemical effect of the Biophosphomag medication on the biochemical blood indicators in rats under oxidative stress conditions

Autor: R. I. Palonko
Jazyk: English<br />Ukrainian
Rok vydání: 2022
Předmět:
Zdroj: Біологія тварин, Vol 24, Iss 3, Pp 39-43 (2022)
Druh dokumentu: article
ISSN: 1681-0015
2313-2191
DOI: 10.15407/animbiol24.03.039
Popis: The study was aimed to examine the effects of the Biophosphomag medication on biochemical parameters of blood under induced oxidative stress in rats. For this purpose, we used 24 animals weighing 200±20 g. The animals were divided into 4 groups of 6 animals in each one and kept on a standard diet with access to water ad libitum. The 1st group was an intact control without oxidative stress and its correction; the 2nd was a control with induced oxidative stress and without its correction. The 3rd group received a 1% solution of magnesium sulfate intragastrically. The animals of the 4th group were administered Biophosphomag (a combined medication of magnesium and phosphorus based on casein) in a dose equivalent to magnesium sulfate by magnesium. Oxidative stress was induced with a single intragastric administration of paracetamol. The results of the serum analysis after the intake of medication showed, on the one hand, a decrease in the activity of the enzymes: alkaline phosphatase, alanine aminotransferase, α-amylase, aspartate aminotransferase, lactate dehydrogenase, glucose and TBA-active compounds concentration (P
Databáze: Directory of Open Access Journals