Autor: |
Debora Glenda Lima de La Roque, Elaine Vieira Santos, Lucca Rocha Policastro, Péricles Natan Mendes da Costa, Mariane Evaristo, Aparecida Yulie Yamamoto, Denise Bergamaschi Giomo, Paula Marilia Afonso Torres, Danielle Cristina Dacanal Gentil, Elaine Cristina Manini Minto, Svetoslav Nanev Slavov, Vagner Fonseca, Claudia Renata dos Santos Barros, Antonio Jorge Martins, Rodrigo Tocantins Calado, Luzia Márcia Romanholi Passos, Maria Carolina Elias, Sandra Coccuzzo Sampaio, Marta Giovanetti, Dimas Tadeu Covas, Luiz Carlos Júnior Alcântara, Simone Kashima |
Jazyk: |
angličtina |
Rok vydání: |
2024 |
Předmět: |
|
Zdroj: |
Journal of Infection and Public Health, Vol 17, Iss 7, Pp 102442- (2024) |
Druh dokumentu: |
article |
ISSN: |
1876-0341 |
DOI: |
10.1016/j.jiph.2024.04.026 |
Popis: |
We aimed to describe the landscape, including molecular, epidemiological, and clinical aspects of CHIKV infections in the Ribeirao Preto region, an area endemic to dengue. We randomly screened 3744 plasma samples that had undergone DENV diagnosis to evaluate CHIKV-RNA using an in-house RT-PCR assay. Positive samples were followed clinically, and RNA samples were submitted to whole genome sequencing. Seventeen cases (0.5 %) were positive for CHIKV-RNA despite being negative for DENV-RNA. Notably, half of the patients experienced prolonged arthralgia lasting more than 90 days. Compared with the healthy control group, leukopenia and thrombocytopenia were observed in all CHIKV-positive individuals with statistically significant P values (P |
Databáze: |
Directory of Open Access Journals |
Externí odkaz: |
|