Dietary aflatoxin B1 induces abnormal deposition of melanin in the corium layer of the chicken shank possibly via promoting the expression of melanin synthesis-related genes

Autor: Yong-li WANG, Chao HUANG, Yang YU, Ri-chun CAI, Yong-chun SU, Zhi-wu CHEN, Mai-qing ZHENG, Huan-xian CUI
Jazyk: angličtina
Rok vydání: 2023
Předmět:
Zdroj: Journal of Integrative Agriculture, Vol 22, Iss 6, Pp 1847-1856 (2023)
Druh dokumentu: article
ISSN: 2095-3119
DOI: 10.1016/j.jia.2023.04.001
Popis: San-Huang chicken is a high-quality breed in China with yellow feather, claw and break. However, the abnormal phenomenon of the yellow shank turning into green shank of San-Huang chicken has been a concern, as it seriously reduces the carcass quality and economic benefit of yellow-feathered broilers. In this study, the cause of this abnormal green skin in shank was systematically investigated. Physiological anatomy revealed that the abnormal skin in shank was primarily due to the deposition of melanin under the dermis. After analyzing multiple potential causes such as heredity (pedigree and genetic markers), environment (water quality monitoring) and feed composition (mycotoxin detection), excessive aflatoxin B1 (AFB1) in feed was screened, accompanied with a higher L-dihydroxy-phenylalanine (L-DOPA) (P170 μg kg–1) indeed induced the abnormal green skin in shank compared to the normal AFB1 content (
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