Oral manifestations of McCune-Albright syndrome

Autor:	Konidena Aravinda, Pamula Ratnakar, Kandakurti Srinivas
Jazyk:	angličtina
Rok vydání:	2013
Předmět:	Albright′s syndrome fibrous dysplasia of the jaws fibroosseous lesion polyostotic fibrous dysplasia Diseases of the endocrine glands. Clinical endocrinology RC648-665 Diseases of the digestive system. Gastroenterology RC799-869
Zdroj:	Indian Journal of Endocrinology and Metabolism, Vol 17, Iss 1, Pp 170-173 (2013)
Druh dokumentu:	article
ISSN:	2230-8210 2230-9500
DOI:	10.4103/2230-8210.107878
Popis:	McCune- Albright Syndrome (MAS) is a rare fibrosseous lesion, characterized by a classic triad of polyostotic fibrous dysplasia (PFD), cafι -au-lait macules (CALM) and underlying endocrinopathies. We present the oral findings of an interesting case of MAS with relevant review of literature. A 30-year-old male presented to us with swelling of both jaws over a period of two years. Cutaneous examination revealed cafι - au - lait macule over the back, crossing the midline. Skeletal survey showed expansile, osteolytic, mixed radiolucent- radiopaque lesions in skull and jaw bones. Serum alkaline phosphatase was elevated (388 IU/L), with normal calcium, phosphorus, parathyroid hormone and 25 hydroxy vitamin D levels. Diagnosis of McCune- Albright syndrome was made and he was treated with parenteral bisphosphonates (intravenous Zoledronate 4 mg) and is under follow up for surgical recontouring of the jaws. Early recognition facilitates better treatment and improves prognosis by reducing the morbidity.
Databáze:	Directory of Open Access Journals
Externí odkaz:	https://doaj.org/article/0c4dfde122244b609ba44152cb3e17b3 Zobrazit plný text záznamu View record in DOAJ Plný text ve formátu PDF