| Autor: |
Krzysztof Woźniak, Oliwia Zegrocka-Stendel, Tomasz Giller, Piotr Cmoch, Maura Malińska, Katarzyna Koziak, Marta Łaszcz, Bogdan Zagrodzki, Kamil Jatczak, Mariusz M. Gruza, Grzegorz Grynkiewicz |
| Jazyk: |
angličtina |
| Rok vydání: |
2013 |
| Předmět: |
|
| Zdroj: |
Molecules, Vol 18, Iss 4, Pp 4389-4402 (2013) |
| Druh dokumentu: |
article |
| ISSN: |
1420-3049 |
| DOI: |
10.3390/molecules18044389 |
| Popis: |
A two-step chemical process for controlled degradation of escin, affording a mixture of olean-12-ene sapogenins, was elaborated and scaled up. The main component of the mixture—protoescigenin—was isolated and purified, in the form of its corresponding monohydrate, without resource to chromatographic methods. This material was further converted into the high purity 3,24;16,22-di-O,O-isopropylidene derivative in a validated large scale laboratory process. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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