Gastrointestinal Complications of Intra-Abdominal Desmoid Tumors: A Case Report and Review of the Literature

Autor: Darcy Morris, Raquel Gonzalez, Jane Cook, Jonathan Metts, Peter Shaw
Jazyk: angličtina
Rok vydání: 2022
Předmět:
Zdroj: Case Reports in Oncology, Vol 15, Iss 2, Pp 515-521 (2022)
Druh dokumentu: article
ISSN: 1662-6575
DOI: 10.1159/000522441
Popis: A 15-year-old male with a mesenteric desmoid tumor and underlying familial adenomatous polyposis presented 2 weeks after initiating sorafenib with severe abdominal pain and chills and was found to have an acute abdomen. Exploratory laparotomy revealed a necrotic, ruptured tumor with impending small bowel obstruction. The patient was later able to resume sorafenib and experienced sustained a radiographic response. It is possible that sorafenib toxicity contributed to tumor rupture yet later provided clinical benefit. Here we review the gastrointestinal complications that are associated with intra-abdominal desmoid tumors and their therapies.
Databáze: Directory of Open Access Journals
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