| Autor: |
Besa Ziso, Tim L. Williams, R. Jon L. Walters, Stephan R. Jaiser, Johannes Attems, Udo C. Wieshmann, A.J. Larner, Anu Jacob |
| Jazyk: |
angličtina |
| Rok vydání: |
2015 |
| Předmět: |
|
| Zdroj: |
Case Reports in Neurology, Vol 7, Iss 1, Pp 95-100 (2015) |
| Druh dokumentu: |
article |
| ISSN: |
1662-680X |
| DOI: |
10.1159/000381944 |
| Popis: |
Three patients with the clinical and investigation features of facial onset sensory and motor neuronopathy (FOSMN) syndrome are presented, one of whom came to a post-mortem examination. This showed TDP-43-positive inclusions in the bulbar and spinal motor neurones as well as in the trigeminal nerve nuclei, consistent with a neurodegenerative pathogenesis. These data support the idea that at least some FOSMN cases fall within the spectrum of the TDP-43 proteinopathies, and represent a focal form of this pathology. |
| Databáze: |
Directory of Open Access Journals |
| Externí odkaz: |
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